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Glyrep (Metformin)

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Glyrep also increases your body's response to insulin, a natural substance that controls the amount of glucose in the blood. Glyrep is used alone or with other medications, including insulin, to treat type 2 diabetes. Glyrep is in a class of drugs called biguanides.

Other names for this medication:
Asoformin, Asoride, Bemet, Cetapin, Conformin, Daocon, Diamin, Dianorm, Diapride, Diform, Dipride, Dokmet, Fortamet, Gamaze, Glidiet, Glimaday, Glimet, Glimid, Glimilex, Glital, Glyciphage, Glycomet, Glyformin, Glyrep, Insumet, Mefinda, Meglipride, Melmet, Mesite, Metadoze, Metneed, Metsig, Minimet, Mintide, Ozomet, Pioglar, Resicon, Rismet, Rosinorm, Rozyformin, Tgmet, Theraformin, Voglinorm, Volabay, Zetfor, Zoform, Zomet

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Also known as: Metformin


Glyrep (metformin) is an oral diabetes medicine that helps control blood sugar levels.

Glyrep is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.

Glyrep is sometimes used together with insulin or other medications, but metformin is not for treating type 1 diabetes.


Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Take Glyrep XR with a meal, unless your doctor tells you otherwise. Some forms of metformin are taken only once daily with the evening meal. Follow your doctor's instructions.

Do not crush, chew, or break an extended-release tablet. Swallow it whole.

Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Shake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Some tablets are made with a shell that is not absorbed or melted in the body. Part of this shell may appear in your stool. This is normal and will not make the medicine less effective.

You may have low blood sugar (hypoglycemia) and feel very hungry, dizzy, irritable, confused, anxious, or shaky. To quickly treat hypoglycemia, eat or drink a fast-acting source of sugar (fruit juice, hard candy, crackers, raisins, or non-diet soda).

Your doctor may prescribe a glucagon injection kit in case you have severe hypoglycemia. Be sure your family or close friends know how to give you this injection in an emergency.

Blood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule.

Glyrep XR is only part of a complete treatment program that may also include diet, exercise, weight control, blood sugar testing, and special medical care. Follow your doctor's instructions very closely.

Store at room temperature away from moisture, heat, and light.

Your doctor may have you take extra vitamin B12 while you are taking Glyrep XR. Take only the amount of vitamin B12 that your doctor has prescribed.

Detailed Glyrep XR dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can cause severe hypoglycemia or lactic acidosis.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Glyrep are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Avoid drinking alcohol. It lowers blood sugar and may increase your risk of lactic acidosis.

metformin and alcohol lactic acidosis

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